{"id":2446,"date":"2019-12-09T08:12:58","date_gmt":"2019-12-09T08:12:58","guid":{"rendered":"https:\/\/wex.dev.rp021.webhelplogin.com\/technology\/publications\/"},"modified":"2023-09-26T22:42:24","modified_gmt":"2023-09-27T05:42:24","slug":"publications","status":"publish","type":"page","link":"https:\/\/wex.dev.rp021.webhelplogin.com\/zh-hans\/technology\/publications\/","title":{"rendered":"\u53d1\u8868\u6587\u7ae0"},"content":{"rendered":"\t\t
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Halneuron\u00ae<\/sup>
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Wong D, Korz W. Tetrodotoxin treatment of mechanical allodynia in rats with oxaliplatin and vincristine-induced neuropathy.<\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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American Pain Society 34th annual scientific meeting
May 13-16, 2015. Palm Springs, CA, USA<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Clifford JL, Salas MM, McIntyre M, Wong D, Korz W. Tetrodotoxin attenuates thermal hyperalgesia in a rat full thickness thermal injury pain model.<\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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American Pain Society 34th annual scientific meeting
May 13-16, 2015. Palm Springs, CA, USA<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Hagen NA, Cantin L, Constant J, Haller T, Blaise G,\u00a0 Ong\u2013Lam M, du Souich P, Korz W, Lapointe B. Tetrodotoxin for moderate to severe cancer-related pain: a multicentre, randomized, double-blind, placebo-controlled, parallel-design trial.<\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Canadian Pain Society 36th annual scientific meeting
May 20-23, 2015. Charlottetown, PEI. Canada<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Goldlust S, Kavoosi M, Korz W, Deck K. Tetrodotoxin for chemotherapy induced neuropathic pain.<\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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American Academy of Pain Management 26th annual clinical meeting
September 17-20, 2015. Washington, DC, USA.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Goldlust S, Kavoosi M, Korz W, Deck K. Tetrodotoxin (TTX) for Chemotherapy Induced Neuropathic Pain (CINP): A Randomized, Double-Blind, Dose-Finding, Placebo Controlled, Multicenter Study.<\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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American Academy of Neurology 68th annual meeting
April 15-21, 2016. Vancouver, BC, Canada<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Ruckle J, Wong D, Kavoosi M, Korz W, Wei H, Zhao F, Spanswick D, Livezey V. The Peripheral Action of Tetrodotoxin: A Translational Research Study. <\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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IASP 16th World Congress on Pain
Sep 26-30, 2016. Yokohama, Japan.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Wong D, Korz W, Wei H, Zhao F, Spanswick D. An Electrophysiological Examination on the Mechanism of Action of Tetrodotoxin for the Treatment of Chemotherapy-induced Neuropathic Pain in a Rat Model of Oxaliplatin-Induced Peripheral Neuropathy.<\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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International Association for the Study of Pain (IASP) World Congress on Pain
September 19-23, 2022. Toronto, Ontario, Canada.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Wong D, Korz W, Awaga Y, Yano M, Fujii R, Natsume T, Hama A, Takamatsu H. Reduced Pain and Regional Brain Activation following Tetrodotoxin (TTX) Treatment in a Cynomolgus Model of Post-operative Pain.<\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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13th Congress of the European Pain Federation (EFIC\u00ae)
September 20-22, 2023. Budapest, Hungary.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\u6709 WEX \u4f5c\u8005\u7684\u51fa\u7248\u7269\u5217\u8868<\/strong><\/h4>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Marcil J, Walczak JS, Guindon J, Ngoc AH, Lu S, Beaulieu P. Antinociceptive effects of tetrodotoxin (TTX) in rodents.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Br J Anaesth. 2006 Jun;96(6):761-8.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Hagen NA, Fisher KM, Lapointe B, du Souich P, Chary S, Moulin D, Sellers E, Ngoc AH; Canadian Tetrodotoxin Study Group. An open-label, multi-dose efficacy and safety study of intramuscular tetrodotoxin in patients with severe cancer-related pain.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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J Pain Symptom Manage. 2007 Aug;34(2):171-82.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Guzm\u00e1n A, Fern\u00e1ndez de Henestrosa AR, Mar\u00edn AP, Ho A, Borroto JI, Carasa I, Pritchard L. Evaluation of the genotoxic potential of the natural neurotoxin Tetrodotoxin (TTX) in a battery of in vitro and in vivo genotoxicity assays.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Mutat Res. 2007 Dec 1;634(1-2):14-24.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Hagen NA, du Souich P, Lapointe B, Ong-Lam M, Dubuc B, Walde D, Love R, Ngoc AH; Canadian Tetrodotoxin Study Group. Tetrodotoxin for moderate to severe cancer pain: a randomized, double blind, parallel design multicenter study.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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J Pain Symptom Manage. 2008 Apr;35(4):420-9.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Hagen NA, Lapointe B, Ong-Lam M, Dubuc B, Walde D, Gagnon B, Love R, Goel R, Hawley P, Ngoc AH, du Souich P. A multicentre open-label safety and efficacy study of tetrodotoxin for cancer pain.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Curr Oncol. 2011 Jun;18(3):e109-16.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Berde CB, Athiraman U, Yahalom B, Zurakowski D, Corfas G, Bognet C. Tetrodotoxin-bupivacaine-epinephrine combinations for prolonged local anesthesia.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Mar Drugs. 2011 Dec;9(12):2717-28.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Hagen NA, Cantin L, Constant J, Haller T, Blaise G, Ong-Lam M, du Souich P, Korz W, Lapointe B. Tetrodotoxin for Moderate to Severe Cancer-Related Pain: A Multicentre, Randomized, Double-Blind, Placebo-Controlled, Parallel-Design Trial.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Pain Res Manag. 2017;2017:7212713.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Kavoosi M, O’Reilly TE, Kavoosi M, Chai P, Engel C, Korz W, Gallen CC, Lester RM. Safety, Tolerability, Pharmacokinetics, and Concentration-QTc Analysis of Tetrodotoxin: A Randomized, Dose Escalation Study in Healthy Adults.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Toxins (Basel). 2020 Aug 9;12(8):511.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Goldlust SA, Kavoosi M, Nezzer J, Kavoosi M, Korz W, Deck K. Tetrodotoxin for Chemotherapy-Induced Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Dose Finding Trial.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Toxins (Basel). 2021 Mar 25;13(4):235.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\u6ca1\u6709WEX \u4f5c\u8005\u7684\u51fa\u7248\u7269\u5217\u8868<\/strong><\/h4>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Gonz\u00e1lez-Cano R, Ruiz-Cantero MC, Santos-Caballero M, G\u00f3mez-Navas C, Tejada M\u00c1, Nieto FR. Tetrodotoxin, a Potential Drug for Neuropathic and Cancer Pain Relief?<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Toxins. 2021 Jul 12;13(7):483.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Berde CB, Athiraman U, Yahalom B, Zurakowski D, Corfas G, Bognet C. Tetrodotoxin-bupivacaine-epinephrine combinations for prolonged local anesthesia.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Mar Drugs. 2011 Dec;9(12):2717-28.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Halneuron\u00ae \u975e\u963f\u7247\u7c7b\u6b62\u75db\u836f\u200b \u6f14\u793a\u6587\u7a3f Wong D, Korz W. Tetrodotoxin t […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":2410,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false},"acf":[],"yoast_head":"\n\u53d1\u8868\u6587\u7ae0 - WEX Pharmaceuticals Inc - Halneuron for Pain Management<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/wex.dev.rp021.webhelplogin.com\/zh-hans\/technology\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u53d1\u8868\u6587\u7ae0 - WEX Pharmaceuticals Inc - Halneuron for Pain Management\" \/>\n<meta property=\"og:description\" content=\"Halneuron\u00ae \u975e\u963f\u7247\u7c7b\u6b62\u75db\u836f\u200b \u6f14\u793a\u6587\u7a3f Wong D, Korz W. 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